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Reparixin
Price range: 77 CAD through 2,800 CAD
Products Details
Product Description
– Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
Web ID
– T4163
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H21NO3S
Citations
– 1. Shi Y, Yu J, Zhang Y, et al. RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway. Biochemical Pharmacology. 2019, 169: 113634.
2. Ma Y T, Zheng L, Zhao C W, et al.Interferon-α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion.Cytokine.2024, 177: 156555.
References
– Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem. 2007 Aug 23;50(17):3984-4002.
CAS Number
– 266359-83-5
Molecular Weight
– C14H21NO3S
Compound Purity
– 0.9989
SMILES
– CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O
Pathway
– Autophagy|||Immunology/Inflammation|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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