Regorafénib N-oxyde (M2)
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Regorafénib N-oxyde (M2)

SKU T10157-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 794 CAD

Products Details

Product Description

– Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).

Web ID

– T10157

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H15ClF4N4O4

References

– Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48.

CAS Number

– 835621-11-9

Molecular Weight

– C21H15ClF4N4O4

Compound Purity

– 0.9803

SMILES

– CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)cc[n+]1[O-]

Target

– Others

Pathway

– MAPK|||Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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