Regorafenib monohydrate
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Regorafenib monohydrate

SKU T1792L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 586 CAD

Products Details

Product Description

– Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively.

Web ID

– T1792L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H17ClF4N4O4

References

– Wilhelm SM, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer, 2011, 129(1), 245-255.

CAS Number

– 1019206-88-2

Molecular Weight

– C21H17ClF4N4O4

Compound Purity

– 0.9969

SMILES

– O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

Target

– Others

Pathway

– MAPK|||Autophagy|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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