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Rebeccamycin
Price range: 712 CAD through 3,168 CAD
Products Details
Product Description
– Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.
Web ID
– T16726
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H21Cl2N3O7
References
– Merchant J, et al. Phase I clinical and pharmacokinetic study of NSC 655649, a rebeccamycin analogue, given in both single-dose and multiple-dose formats. Clin Cancer Res. 2002 Jul;8(7):2193-201.
CAS Number
– 93908-02-2
Molecular Weight
– C27H21Cl2N3O7
SMILES
– O=C1C2=C3C(N(C=4C3=CC=CC4Cl)[C@@]5(O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)[H])=C6C(=C2C(=O)N1)C=7C(N6)=C(Cl)C=CC7
Target
– PD-1/PD-L1
Pathway
– Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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