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Products Details
Product Description
– RARα antagonist 1 (compound 21) is an orally active and selective retinoic acid receptor α(RARα) antagonist, with the IC50 of 4.6nM[1].
Web ID
– HY-156280
Shipping
– Room temperature
Molecular Formula
– C26H23NO4
References
– [1]Al Noman MA, et al. Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception [published online ahead of print, 2023 Sep 25]. Eur J Med Chem. 2023;261:115821.
Molecular Weight
– 413.47
SMILES
– OC(C1=CC=C(NC(C(C=C2)=CC3=C2OC(C)(C)C=C3C4=CC=C(C)C=C4)=O)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– RAR/RXR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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