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Ralfinamide (mesylate)

Products Details

Product Description

– Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain[1][2].

Web ID

– HY-101437A

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C18H23FN2O5S

References

– [1]Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139(2):293-305.|[2]Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.

CAS Number

– 202825-45-4

Molecular Weight

– 398.45

SMILES

– C[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O.CS(=O)(O)=O

Clinical Information

– Phase 3

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Sodium Channel

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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