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Products Details
Product Description
– RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.
Web ID
– T6296
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H16F6N6O
References
– AACR Meeting Abstracts 2008;2008:4876.
CAS Number
– 927880-90-8
Molecular Weight
– C24H16F6N6O
Compound Purity
– 0.9956
SMILES
– Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2cc(Oc3ccnc(c3)-c3ncc([nH]3)C(F)(F)F)ccc12
Pathway
– Angiogenesis|||Autophagy|||Apoptosis|||Tyrosine Kinase/Adaptors|||MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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