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(Rac)-VU 6008667
Price range: 51 CAD through 650 CAD
Products Details
Product Description
– (Rac)-VU 6008667 is a selective negative allosteric modulator of the muscarinic acetylcholine receptor subtype 5 (M5 NAM), with an IC50 of 1.8 μM and a pIC50 of 5.75, exhibiting high CNS penetration.
Web ID
– T12679
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H17ClF2N2O2
References
– McGowan KM, et al. Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.
CAS Number
– 2092917-63-8
Molecular Weight
– C24H17ClF2N2O2
Compound Purity
– 0.9883
SMILES
– C(=O)(N1C2(C=3C(C(=O)N2CC1)=CC=CC3)C4=CC(C)=C(Cl)C=C4)C5=CC(F)=C(F)C=C5
Target
– Proton pump|||Antibacterial|||Autophagy|||Cytochromes P450
Pathway
– Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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