(Rac)-SAR131675
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(Rac)-SAR131675

SKU T3691-1 mg Category Brand:

Price range: 48 CAD through 795 CAD

Products Details

Product Description

– (Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion.

Web ID

– T3691

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H22N4O4

References

– Alam A, et al. Mol Cancer Ther, 2012, 11(8), 1637-1649.

CAS Number

– 1092539-44-0

Molecular Weight

– C18H22N4O4

Compound Purity

– 0.9834

SMILES

– CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#C[C@@](C)(O)COC

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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