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Products Details
Product Description
– (Rac)-RK-682, a racemate of RK-682, is a protein tyrosine phosphatases (PTPases) inhibitor. (Rac)-RK-682 inhibits protein tyrosine phosphatase 1B (PTP-1B), low molecular weight protein tyrosine phosphatases (LMW-PTP), and cell division cycle 25B (CDC-25B) with IC50s of 8.6 μM, 12.4 μM, and 0.7 μM, respectively[1].
Web ID
– HY-135564B
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H36O5
References
Р[1]V̢nia M T Carneiro, et al. Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues. Eur J Med Chem. 2015 Jun 5;97:42-54.
CAS Number
– 154639-24-4
Molecular Weight
– 368.51
SMILES
– O=C1OC(CO)C(O)=C1C(CCCCCCCCCCCCCCC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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