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Product Description
– (Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with IC50 values of 10 nM and 68 nM, respectively, and demonstrates good metabolic stability [1].
Web ID
– T12663
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H27NO3
References
– Ye XY, et al. Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3′-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J Med Chem. 2017 Jun 22;60(12):4932-4948.
Molecular Weight
– C21H27NO3
SMILES
– OC1[C@H]2C[C@@H]3[C@@](C4=CC=CC=C4)(CC(N5CC(O)C5)=O)[C@@H](CC1C3)C2
Target
– Chloride channel
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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