R1487 Hydrochloride
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R1487 Hydrochloride

SKU T7162-2 mg Category Brand:

Price range: 106 CAD through 171 CAD

Products Details

Product Description

– R1487 Hydrochloride is an orally available, selective and potent inhibitor of mitogen-activated protein kinase (p38α) for the study of metabolic diseases.

Web ID

– T7162

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H19ClF2N4O3

References

– Goldstein DM, Soth M, Gabriel T,et al.Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase[J].J Med Chem. 2011 Apr 14;54(7):2255-65.

CAS Number

– 449808-64-4

Molecular Weight

– C19H19ClF2N4O3

Compound Purity

– 0.9942

SMILES

– Cl.O=C1C(OC2=CC=C(F)C=C2F)=CC=3C=NC(=NC3N1C)NC4CCOCC4

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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