Products Details

Product Description

– (R)-MIK665 is the less active enantiomer of MIK665. MIK665 is a special Mcl-1 inhibitor with an IC50 of 1.81 nM.

Web ID

– HY-112218A

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C47H44ClFN6O6S

References

– [1]Andras Kotschy, et al. New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them. EP2886545A1.

CAS Number

– 1799831-02-9

Molecular Weight

– 875.41

SMILES

– OC([C@@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[C@@]([C@@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O.[R].[R]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Bcl-2 Family

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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