(R)-GNE-140
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(R)-GNE-140

SKU T4295-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 107 CAD through 1,112 CAD

Products Details

Product Description

– (R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.

Web ID

– T4295

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H23ClN2O3S2

Citations

– 1. Zhang Y T, Xing M L, Fang H H, et al.Effects of lactate on metabolism and differentiation of CD4+T cells.Molecular Immunology.2023, 154: 96-107.

References

– Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7(10):896-901.

CAS Number

– 2003234-63-5

Molecular Weight

– C25H23ClN2O3S2

Compound Purity

– 0.9891

SMILES

– OC1=C(Sc2ccccc2Cl)C(=O)N[C@@](C1)(c1ccsc1)c1ccc(cc1)N1CCOCC1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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