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Products Details
Product Description
– (R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1/2/5/7/9 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.
Web ID
– T12617
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H32Cl3N7O
References
– Bettayeb K, et al. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene. 2008 Oct 2;27(44):5797-807.
CAS Number
– 1786438-30-9
Molecular Weight
– C24H32Cl3N7O
Compound Purity
– 0.9933
SMILES
– Cl.Cl.Cl.CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1
Target
– Others
Pathway
– Cell Cycle/Checkpoint|||Apoptosis
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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