(R)-(+)-Bay-K-8644

$118$1,350

Products Details

Product Description

– (R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM).

Web ID

– HY-15125

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C16H15F3N2O4

References

– [1]Zhu HL, et al. Antagonistic actions of S(-)-Bay K 8644 on cyclic nucleotide-induced inhibition of voltage-dependent Ba(2+) currents in guinea pig gastric antrum. Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):609-15.|[2]Sidaway P, et al. L-type Ca2+ channel sparklets revealed by TIRF microscopy in mouse urinary bladder smooth muscle. PLoS One. 2014 Apr 3;9(4):e93803.

CAS Number

– 98791-67-4

Molecular Weight

– 356.30

Compound Purity

– 99.69

SMILES

– CC1=C([N+]([O-])=O)[C@H](C2=C(C(F)(F)F)C=CC=C2)C(C(OC)=O)=C(C)N1

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : ≥ 300 mg/mL

Target

– Calcium Channel

Isoform

– L-type calcium channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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