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Quisinostat
Price range: 86 CAD through 1,021 CAD
Products Details
Product Description
– Quisinostat (JNJ-26481585) (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7.
Web ID
– T6055
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H26N6O2
Citations
– 1. Lidsky M E, Wang Z, Lu M, et al. Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies. npj Precision Oncology. 2022, 6(1): 1-17.
References
– Arts J, et al. JNJ-26481585, a novel “second-generation” oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Clin Cancer Res. 2009 Nov 15;15(22):6841-51.
CAS Number
– 875320-29-9
Molecular Weight
– C21H26N6O2
Compound Purity
– 0.9801
SMILES
– Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
Pathway
– Chromatin/Epigenetic|||Apoptosis|||Autophagy|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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