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Quinagolide (hydrochloride)
$420 – $2,520
Products Details
Product Description
– Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer[1][2].
Web ID
– HY-13736A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H34ClN3O3S
References
– [1]Trouillas J, et al. Inhibitory effects of the dopamine agonists quinagolide (CV 205-502) and bromocriptine on prolactin secretion and growth of SMtTW pituitary tumors in the rat. Endocrinology. 1994 Jan;134(1):401-10.|[2]Iampietro C, et al. Quinagolide Treatment Reduces Invasive and Angiogenic Properties of Endometrial Mesenchymal Stromal Cells. Int J Mol Sci. 2022 Feb 4;23(3):1775.
CAS Number
– 94424-50-7
Molecular Weight
– 432.02
Compound Purity
– 99.00
SMILES
– OC1=C2C(C[C@](N(CCC)C[C@@H](NS(N(CC)CC)(=O)=O)C3)([H])[C@@]3([H])C2)=CC=C1.Cl
Clinical Information
– Launched
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 3.85 mg/mL (ultrasonic)
Target
– Akt;Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
