PYR-41
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PYR-41

SKU T6629-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 1,728 CAD

Products Details

Product Description

– PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.

Web ID

– T6629

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H13N3O7

Citations

– 1. Kosmider O, Possémé C, Templé M, et al.VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation.Nature Communications.2024, 15(1): 910. 2. Qiu Q, He Z, Liu J, et al.Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein.PLoS pathogens.2025, 21(1): e1012897.

References

– Yang Y, et al. Cancer Res, 2007, 67(19), 9472-9481.

CAS Number

– 418805-02-4

Molecular Weight

– C17H13N3O7

Compound Purity

– 0.9825

SMILES

– CCOC(=O)c1ccc(cc1)N1NC(=O)C(=Cc2ccc(o2)[N+]([O-])=O)C1=O

Pathway

– Ubiquitination|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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