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Products Details
Product Description
– PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3.7 μM, 3.4 μM, 0.4 μM, 1.5 μM, and 0.3 μM, respectively. PXS-6302 hydrochloride penetrates easily through the skin and is able to reduce collagen accumulation, significantly improving the appearance of scars.
Web ID
– T60438L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H11ClF3NO2S
References
– Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13(1):5555.
CAS Number
– 2584947-79-3
Molecular Weight
– C10H11ClF3NO2S
Compound Purity
– 0.9989
SMILES
– S(C(/C(=C/CN)/F)(F)F)(=O)(=O)C1=CC=CC=C1.Cl
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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