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PXS-6302 (hydrochloride)
SKU
HY-151499A-1 mg
Category Reference compound
Tags Inflammation/Immunology, Monoamine Oxidase, Neuronal Signaling
$312 – $3,188
Products Details
Product Description
– PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].
Web ID
– HY-151499A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C10H11ClF3NO2S
References
– [1]Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13(1):5555.
CAS Number
– 2584947-79-3
Molecular Weight
– 301.71
Compound Purity
– 99.83
SMILES
– NC/C=C(C(F)(S(=O)(C1=CC=CC=C1)=O)F)F.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.