PXS-4728A

$57$1,050

Products Details

Product Description

– PXS-4728A (BI-1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO). PXS-4728A ameliorates chronic obstructive pulmonary disease in mice[1].

Web ID

– HY-112726

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H22ClFN2O2

References

– [1]A G Jarnicki, et al. The Inhibitor of Semicarbazide-Sensitive Amine Oxidase, PXS-4728A, Ameliorates Key Features of Chronic Obstructive Pulmonary Disease in a Mouse Model. Br J Pharmacol. 2016 Nov;173(22):3161-3175.

CAS Number

– 1478364-68-9

Molecular Weight

– 316.80

Compound Purity

– 99.66

SMILES

– O=C(NC(C)(C)C)C1=CC=C(OC/C(CN)=C/F)C=C1.Cl

Clinical Information

– Phase 2

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 250 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Target

– Monoamine Oxidase

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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