PTC-028
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PTC-028

SKU T16680-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 2,432 CAD

Products Details

Product Description

– PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.

Web ID

– T16680

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H12F5N5

References

– Dey A, et al. Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer. Mol Cancer Ther. 2018 Jan;17(1):39-49.

CAS Number

– 1782970-28-8

Molecular Weight

– C19H12F5N5

Compound Purity

– 0.9825

SMILES

– Cc1nc2cc(F)c(F)cc2n1-c1cncc(Nc2ccc(cc2)C(F)(F)F)n1

Target

– Drug-Linker Conjugates for ADC

Pathway

– DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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