PS423

SKU T24676-1 mg Category Brand:

Price range: 187 CAD through 4,576 CAD

Products Details

Product Description

– PS423 (PS210AM) is a substrate-selective inhibitor of PDK1 and a selective PDK1 activator that inhibits the phosphorylation and activation of S6K, and is used in the study of endocrine and metabolic disorders.

Web ID

– T24676

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H23F3O9

References

– Busschots K, Lopez-Garcia LA, Lammi C, Stroba A, Zeuzem S, Piiper A, Alzari PM, Neimanis S, Arencibia JM, Engel M, Schulze JO, Biondi RM. Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site. Chem Biol. 2012 Sep 21;19(9):1152-63. doi: 10.1016/j.chembiol.2012.07.017. PubMed PMID: 22999883.

CAS Number

– 1221964-37-9

Molecular Weight

– C25H23F3O9

Compound Purity

– 0.9926

SMILES

– O=C(OCOC(=O)C(C(=O)OCOC(=O)C)C(C=1C=CC=CC1)CC(=O)C2=CC=C(C=C2)C(F)(F)F)C

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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