Protosappanin B
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Protosappanin B

SKU T6S1780-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 107 CAD through 312 CAD

Products Details

Product Description

– 1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.

Web ID

– T6S1780

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H16O6

Citations

– 1. Pyun B J, Jo K, Lee J Y, et al. Caesalpinia sappan Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells. Antioxidants. 2022, 11(11): 2256.

References

– Zeng K W , Liao L X , Zhao M B , et al. Protosappanin B protects PC12 cells against oxygen–glucose deprivation-induced neuronal death by maintaining mitochondrial homeostasis via induction of ubiquitin-dependent p53 protein degradation[J]. European Journal of Pharmacology, 2015, 751:13-23.

CAS Number

– 102036-29-3

Molecular Weight

– C16H16O6

Compound Purity

– 0.9876

SMILES

– OCC1(O)COc2cc(O)ccc2-c2cc(O)c(O)cc2C1

Pathway

– Apoptosis

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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