PROTAC-O4I2
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PROTAC-O4I2

SKU T74186-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 86 CAD through 4,128 CAD

Products Details

Product Description

– PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.

Web ID

– T74186

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H29ClN6O5S

References

– Rodrigo A Gama-Brambila, et al. A PROTAC targets splicing factor 3BCell Chem Biol. 2021 Nov 18;28(11):1616-1627.e8.

CAS Number

– 2785323-62-6

Molecular Weight

– C29H29ClN6O5S

Compound Purity

– 0.9745

SMILES

– O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCNC(=O)C=4N=C(NC5=CC=C(Cl)C=C5)SC4

Pathway

– Apoptosis|||PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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