Download Files:
Products Details
Product Description
– PROTAC EGF Rdegrader 10 (Compound B56) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR) with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 37 nM and degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibiting the proliferation of BaF3 wild-type and EGFR mutants with an IC50 of less than 150 nM.
Web ID
– T88273
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H65ClN10O7S
CAS Number
– 3034244-56-6
Molecular Weight
– C49H65ClN10O7S
SMILES
– O=C1NC(=O)C(C2=CC=C(C=C2)N3CCC(OCCN4CCN(CC4)C5CCN(C6=CC(OC)=C(C=C6CC)NC7=NC=C(Cl)C(=N7)NC8=CC=C(OC)C=C8N(C)S(=O)(=O)C)CC5)CC3)CC1
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
CDK ligand for PROTAC hydrochloride
Price range: 498 CAD through 3,170 CAD
1000 in stock
