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Products Details
Product Description
– PROTAC eDHFR Degrader-1 is a PROTAC that is effective degradation of eDHFR-YFP, various POIs-including YFP and Luciferase[1].
Web ID
– HY-149678
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H44N8O10
References
– [1]Jean M. Etersque, Regulation of eDHFR-tagged proteins with trimethoprim PROTACs.Nat Commun. 2023; 14: 7071.
CAS Number
– 2849442-92-6
Molecular Weight
– 748.78
SMILES
– NC1=C(CC2=CC(OC)=C(OCCCC(NCCOCCOCCNC3=CC=CC(C(N4C5CCC(NC5=O)=O)=O)=C3C4=O)=O)C(OC)=C2)C=NC(N)=N1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– PROTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
