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Products Details
Product Description
– PROTAC CDK9/CycT1 Degrader-2 is a inhibitor of CDK9, with the IC50 of 45 nM[1].
Web ID
– HY-156795
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H36N4O6S2
References
– [1]Harald Gollnick, et al. Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs. Expert Opin Pharmacother. 2008 Oct;9(15):2699-706.
Molecular Weight
– 612.76
SMILES
– O=C1OC2=CC(OCCCN3CCC(CC3)C(NC4=NC=C(S4)SCC5=NC=C(O5)C(C)(C)C)=O)=CC(O)=C2C(C)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK9
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
