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Products Details
Product Description
– PROTAC BTK Degrader-1, a powerful, selective, and orally bioavailable degrader of PROTAC BTK, demonstrates effective reduction in BTK protein levels and tumor suppression. It exhibits IC50 values of 34.51 nM for BTK WT and 64.56 nM for BTK-481S, highlighting its potency and efficacy in targeting and diminishing BTK protein abundance [1].
Web ID
– T74636
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C43H43N9O4
CAS Number
– 2801715-13-7
Molecular Weight
– C43H43N9O4
SMILES
– Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCN(CC1)C1CCN(CC#Cc2ccc3C(=O)N(Cc3c2)C2CCC(=O)NC2=O)CC1
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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