PROTAC BRD4 Degrader-5

SKU T36242-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 453 CAD through 3,184 CAD

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– PROTAC BRD4 Degrader-5 is a PROTAC that efficiently degrades BRD4 in HER2-positive and -negative breast cancer cell lines, and is formed by linking von Hippel-Lindau ligand to BRD4 ligand.

Web ID

– T36242

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C50H62ClN9O8S2

References

– Mar? A Maneiro, et al. Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4. ACS Chem Biol. 2020 Jun 19;15(6):1306-1312.

CAS Number

– 2409538-70-9

Molecular Weight

– C50H62ClN9O8S2

SMILES

– CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

Pathway

– PROTAC|||Chromatin/Epigenetic

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.