PROTAC BRD4 Degrader-12
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PROTAC BRD4 Degrader-12

SKU T74125-5 mg Category Brand:

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Products Details

Product Description

– PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC that links von Hippel-Lindau and BRD4 ligands. When conjugated with STEAP1 and CLL1 antibodies, this compound effectively degrades BRD4 protein in PC3 prostate cancer cells, demonstrating potent activity with DC50 values of 0.39 nM and 0.24 nM, respectively [1].

Web ID

– T74125

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C62H77F2N9O12S4

CAS Number

– 2417370-90-0

Molecular Weight

– C62H77F2N9O12S4

SMILES

– CC(OC(=O)O[C@@H]1C[C@H](N(C1)C(=O)[C@@H](NC(=O)CCCCCCCCCCNC(=O)c1cc2N(Cc3c[nH]c4c3c(cn(C)c4=O)-c2cc1CS(C)(=O)=O)c1ncc(F)cc1F)C(C)(C)C)C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)SS(C)(=O)=O

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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