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Products Details
Product Description
– PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
Web ID
– T8745
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C48H54F2N10O10S
References
– Han X R , Chen L , Wei Y , et al. Discovery of Selective Small Molecule Degraders of BRAF-V600E[J]. Journal of Medicinal Chemistry, 2020, XXXX(XXX).
CAS Number
– 2417296-84-3
Molecular Weight
– C48H54F2N10O10S
Compound Purity
– 0.9943
SMILES
– FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(C(CCOCCOCCOCCNC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O
Pathway
– MAPK|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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