PROTAC BET degrader-2

SKU T12559-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 637 CAD through 1,872 CAD

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins, with an IC50 of 9.6 nM.

Web ID

– T12559

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C41H42N10O6

References

– Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

CAS Number

– 2093388-33-9

Molecular Weight

– C41H42N10O6

SMILES

– O=C(NCCCC=1C=CC=C2C(=O)N(CC21)C3C(=O)NC(=O)CC3)C4=NC=5NC=6C=C(C(OC)=CC6C5C(=N4)NC7=CC(=NN7CC)C8CC8)C=9C(=NOC9C)C

Target

– Aurora Kinase

Pathway

– PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.