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Products Details
Product Description
– PROTAC BET Degrader-10 (WO2017007612A1, example 37) is a highly efficient and selective small molecule compound designed to degrade BET protein BRD4. PROTAC BET Degrader-10 functions by utilizing specific ligands that connect Cereblon and BRD4, with a DC 50 value of 49 nM.
Web ID
– T39374
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H39ClN8O6S
References
– James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.
CAS Number
– 1957234-97-7
Molecular Weight
– C39H39ClN8O6S
SMILES
– Cc1nnc2[C@H](CC(=O)NCCCCCC(=O)NCc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |c:41|
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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