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Prochloraz
$50 – $55
Products Details
Product Description
– Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC50 of 1 μM[1][2].
Web ID
– HY-B0845
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H16Cl3N3O2
References
– [1]E Antignac, et al. Prochloraz as potent inhibitor of benzo[a]pyrene metabolism and mutagenic activity in rat liver fractions. Toxicol Lett. 1990 Dec;54(2-3):309-15.|[2]Anne Marie Vinggaard, et al. Prochloraz: an imidazole fungicide with multiple mechanisms of action. Int J Androl. 2006 Feb;29(1):186-92.
CAS Number
– 67747-09-5
Molecular Weight
– 376.67
Compound Purity
– 99.77
SMILES
– O=C(N1C=CN=C1)N(CCC)CCOC2=C(Cl)C=C(Cl)C=C2Cl
Clinical Information
– No Development Reported
Research Area
– Infection; Endocrinology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Androgen Receptor;Aryl Hydrocarbon Receptor;Estrogen Receptor/ERR;Fungal
Pathway
– Anti-infection;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
