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Products Details
Product Description
– PRMT5-IN-21 (compound 1) is a potent cyclonucleoside PRMT5 inhibitor[1].
Web ID
– HY-150081
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H18F2N6O3
References
– [1]Kawamura S, et al. Design and synthesis of unprecedented 9- and 10-membered cyclonucleosides with PRMT5 inhibitory activity. Bioorg Med Chem. 2022 Jul 15;66:116820.
Molecular Weight
– 404.37
SMILES
– FC1=C(F)C=CC([C@@H]2[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C(N=CN=C5N)=C5N=C4NCC2)O3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– PRMT5
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
