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Pravastatin (sodium)

$42$172

Products Details

Product Description

– Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

Web ID

– HY-B0165A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture and light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H35NaO7

Citations

– Cell Syst. 2018 Apr 25;6(4):424-443.e7.|Front Cell Dev Biol. 2022 Mar 3;10:806081.|Research Square Preprint. 2022 Feb.|Front Cell Dev Biol. 2020 May 28;8:404.

References

– [1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.

CAS Number

– 81131-70-6

Molecular Weight

– 446.51

Compound Purity

– 99.49

SMILES

– O[C@@H](C[C@@H](O)CC(O[Na])=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O

Clinical Information

– Launched

Research Area

– Cardiovascular Disease; Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL

Target

– Autophagy;Ferroptosis;HMG-CoA Reductase (HMGCR)

Pathway

– Apoptosis;Autophagy;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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