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Pravastatin (sodium)
SKU
HY-B0165A-10 mg
Category Natural Products
Tags Apoptosis;Autophagy;Metabolic Enzyme/Protease, Autophagy;Ferroptosis;HMG-CoA Reductase (HMGCR), Cardiovascular Disease; Cancer
$42 – $172
Products Details
Product Description
– Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Web ID
– HY-B0165A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H35NaO7
Citations
– Cell Syst. 2018 Apr 25;6(4):424-443.e7.|Front Cell Dev Biol. 2022 Mar 3;10:806081.|Research Square Preprint. 2022 Feb.|Front Cell Dev Biol. 2020 May 28;8:404.
References
– [1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.
CAS Number
– 81131-70-6
Molecular Weight
– 446.51
Compound Purity
– 99.49
SMILES
– O[C@@H](C[C@@H](O)CC(O[Na])=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Target
– Autophagy;Ferroptosis;HMG-CoA Reductase (HMGCR)
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.