PP5-IN-1

$195$1,450

Products Details

Product Description

– PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1].

Web ID

– HY-155374

Shipping

– Room temperature

Molecular Formula

– C18H18N2O3S

References

– [1]Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12.

CAS Number

– 1022417-69-1

Molecular Weight

– 342.41

SMILES

– O=S(NC1=CC=C(CC2=CC=CC=C2)C=C1)(C3=C(C)ON=C3C)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Apoptosis;Phosphatase

Pathway

– Apoptosis;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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