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Products Details
Product Description
– Posenacaftor (PTI-801) is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF)[1].
Web ID
– HY-109187
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H27NO5
References
– [1]Benjamin Kopp, et al. Compositions et procédés pour améliorer la fonction cftr dans des cellules affectées par la fibrose kystique. Patent WO2019156946.|[2]Posenacaftor (PTI-801)
CAS Number
– 2095064-05-2
Molecular Weight
– 445.51
SMILES
– O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C5CCOCC5)C)=C14)O
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CFTR
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
