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Pomalidomide-C3-NH2 (hydrochloride)
SKU
HY-131888-10 mg
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
$75 – $200
Products Details
Product Description
– Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Web ID
– HY-131888
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H19ClN4O4
References
– [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.|[2]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.
CAS Number
– 2154342-45-5
Molecular Weight
– 366.80
Compound Purity
– 95.38
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCN)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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