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Products Details
Product Description
– Pomalidomide-5-OH (5-hydroxy pomalidomide) is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTAC[1].
Web ID
– HY-123324
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H11N3O5
References
– [1]Matthew Hoffmann, et al. Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration. Cancer Chemother Pharmacol. 2013 Feb;71(2):489-501.
CAS Number
– 1547162-41-3
Molecular Weight
– 289.24
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(O)=C3N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
