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Products Details
Product Description
– Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)
Web ID
– TP1341
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C43H74N14O11
Citations
– 1. Cui R, Zhang J, Liu X, et al.Dronedarone Enhances the Antibacterial Activity of Polymyxin B and Inhibits the Quorum Sensing System by Interacting with LuxS.ACS Infectious Diseases.2024
References
– Tsubery H, et al. Structure-function studies of polymyxin B nonapeptide: implications to sensitization of gram-negative bacteria. J Med Chem. 2000 Aug 10;43(16):3085-92.
CAS Number
– 86408-36-8
Molecular Weight
– C43H74N14O11
SMILES
– C([C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCN)C(=O)N[C@@H](CCN)C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC[C@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCN)=O)C(=O)N[C@@H](CCN)C(=O)N1)[H])C2=CC=CC=C2
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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