Polmacoxib

SKU T21294-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 949 CAD

Products Details

Product Description

– Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.

Web ID

– T21294

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16FNO4S

References

– Kim SH, Margalit O, Katoh H,et al. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Invest New Drugs. 2014 Aug 3. [Epub ahead of print] PubMed PMID: 25085205.

CAS Number

– 301692-76-2

Molecular Weight

– C18H16FNO4S

Compound Purity

– 0.9849

SMILES

– CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O

Pathway

– Immunology/Inflammation|||Neuroscience|||Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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