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PNU-EDA-Gly5
2,432 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– PNU-EDA-Gly5 is a DNA topoisomerase I inhibitor-based oligo-glycine linker-payload used for the synthesis of antibody-drug conjugates (ADCs). It consists of the DNA topoisomerase I inhibitor PNU-159682 and the linker EDA-Gly5.
Web ID
– T39373
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C43H54N8O17
References
– Quintieri L, et al. Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.
CAS Number
– 1957223-28-7
Molecular Weight
– C43H54N8O17
SMILES
– [H][C@]12C[C@H](O[C@H]3C[C@@](O)(Cc4c(O)c5C(=O)c6cccc(OC)c6C(=O)c5c(O)c34)C(=O)NCCNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN)O[C@@H](C)[C@@]1([H])O[C@]1([H])[C@@H](OC)OCCN21
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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