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PMPA (NMDA antagonist)

Products Details

Product Description

– PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].

Web ID

– HY-107698

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C6H13N2O5P

References

– [1]Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9.

CAS Number

– 113919-36-1

Molecular Weight

– 224.15

SMILES

– O=C(C1NCCN(CP(O)(O)=O)C1)O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– iGluR

Isoform

– NMDA Receptor

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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