PLK1-IN-9
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PLK1-IN-9

SKU T87975-10 mg Category Brand:

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Products Details

Product Description

– PLK1-IN-9 (Compound M2), a polo-like kinase 1 (PLK1) inhibitor, targets the PLK proteins modified with peptides 1010pT, cdc25c, and PBIP, exhibiting IC50 values of 1.6, 0.8, and 1.4 μM, respectively. This compound effectively inhibits the proliferation of various cancer cell lines including HeLa, HL60, SNU387/499, and HepG2, demonstrating cytotoxic effects and inducing apoptosis. Additionally, PLK1-IN-9 has been shown to suppress tumor growth in a HepG2 xenograft mouse model.

Web ID

– T87975

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H7F3N4O2

CAS Number

– 893772-67-3

Molecular Weight

– C12H7F3N4O2

SMILES

– O=C1N=C2C(=NC=3C=C(C=CC3N2C)C(F)(F)F)C(=O)N1

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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