PKSI-527

$110$1,025

Products Details

Product Description

– PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1].

Web ID

– HY-123133

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C25H32ClN3O4

References

– [1]Fujimori Y, et al. Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice. Agents Actions. 1993 May;39(1-2):42-8.

CAS Number

– 128837-71-8

Molecular Weight

– 473.99

Compound Purity

– 98.08

SMILES

– NC[C@@H]1CC[C@H](CC1)C(N[C@H](C(NC2=CC=C(C=C2)CC(O)=O)=O)CC3=CC=CC=C3)=O.Cl

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Ser/Thr Protease

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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