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Products Details
Product Description
– PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times.
Web ID
– T35579
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H32ClN3O4
CAS Number
– 128837-71-8
Molecular Weight
– C25H32ClN3O4
SMILES
– [C@@H](CC1=CC=CC=C1)(NC(=O)[C@H]2CC[C@H](CN)CC2)C(NC3=CC=C(CC(O)=O)C=C3)=O.Cl
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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