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Products Details
Product Description
– PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations.
Web ID
– HY-145937
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H22N2S
References
– [1]Bauer MR, et al. Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ACS Chem Biol. 2020 Mar 20;15(3):657-668.
CAS Number
– 2413987-20-7
Molecular Weight
– 334.48
Compound Purity
– 98.50
SMILES
– CC1=CC=C(C2=CC3=C(C=C2)C4=C(C=CC(CNC)=C4)N3CC)S1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic)
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.