PK68
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PK68

SKU T12493-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 125 CAD through 2,336 CAD

Products Details

Product Description

– PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90 nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis.

Web ID

– T12493

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H24N4O3S

References

– Hou J, et al. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis. Cell Death Dis. 2019 Jun 24;10(7):493.

CAS Number

– 2173556-69-7

Molecular Weight

– C22H24N4O3S

Compound Purity

– 0.9809

SMILES

– CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(C)c(NC(=O)OC2CCCCC2)c1

Target

– Mitochondrial Metabolism

Pathway

– Apoptosis|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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